Proof-of-concept trial in a single patient shows that cells can survive transplantation without immunosuppression ...

A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large-scale gene-silencing structures inside cells, and what happens when that process breaks down. The ...

Cardiovascular disease remains the leading cause of mortality worldwide, necessitating deeper insights into its molecular ...

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

Cell and gene therapies (CGTs) represent the cutting edge of drug discovery. 1 These are amongst the most advanced medical treatments, specifically designed to correct the root genetic cause of an ...

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, ...

Rapidly testing hundreds of thousands of DNA sequences, scientists identified specific genetic variations contributing to blood pressure, cholesterol, and blood sugar.

The Scottish Medicines Consortium (SMC) has accepted exagamglogene autotemcel (Casgevy, Vertex Pharmaceuticals) for use within NHS Scotland to treat sickle cell disease (SCD) in patients aged 12 years ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message (mRNA), which is then converted into a protein. Although DNA remains the same ...