The immune system relies on specialized “effector” T cells to fight off pathogens. However, in chronic infections such as cancer or HIV, the perpetual activation of these cells can turn them into ...
A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called P-bodies, providing a potential means of controlling cell identity.
A chronological map of the fetal brain reveals when key cells emerge and provides clues about autism and cancer.
“Our findings suggest a role for NSD2 in maintaining MM cell identity, with potential implications for future therapeutic strategies based on targeting of NSD2.” “Our findings suggest a role for NSD2 ...
The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" ...
All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on. This coordination is ...
A new research paper was published in Oncotarget, Volume 16, on March 21, 2025, titled "NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma." Researchers Andrea ...
A new study reveals that reprogramming specialized cells to become different types of cells, a key process in regenerative medicine, faces a major hurdle. The challenge lies in the DNA methylation ...