Researchers have discovered that mutations in the FOXJ3 gene act as a "master switch" failure, disrupting how the brain builds its layers and leading to FCD, a primary cause of drug-resistant epilepsy ...

Halassa writes in the context of a broader research program he calls algorithmic psychiatry, which argues that mental illness ...

The cerebral cortex, the brain's outermost region responsible for higher cognitive functions, depends on a highly ordered, layered structure. Its proper development requires newly generated neurons to ...

A new study finds key differences in the development of the cortex between autistic boys and girls ages 2-13. The study found sex-specific changes in the thickness of the outer layer of the brain, ...

Malformations of cortical development are commonly associated with epilepsy and intellectual disabilities. Polymicrogyria is one of the most frequent cortical malformations but remains largely ...

May 7, 2008 (Washington, DC) — A large neuroimaging study found that in attention deficit/hyperactivity disorder (ADHD), brain development follows a normal trajectory, but maturation of the prefrontal ...

Researchers in Japan built a miniature human brain circuit using fused stem-cell–derived organoids, allowing them to watch the thalamus and cortex interact in real time. They found that the thalamus ...

Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...