The development of robust clinical trial methodologies increasingly relies on advanced statistical frameworks for model selection and the characterisation of dose–response relationships. With modern ...
Stylized curves that illustrate the linear, threshold, and hormetic dose-response models for carcinogens. The central pillar upon which toxicological assessments are built is the dose-response ...
The role of radiation dose-dependent enhancement of fatty acid oxidation in radiation surviving/resistant lung cancer cells. This is an ASCO Meeting Abstract from the 2020 ASCO Annual Meeting I. This ...
Fearn, Tom, Strlic, Matija, and Liu, Yun. 2021. "Dose-response modelling for the discolouration of iron gall ink on paper." from Transcending Boundaries: Integrated Approaches to Conservation. ICOM-CC ...
“For if one drinks much from a bottle marked ‘poison,’ it’s almost certain to disagree with one sooner or later.” —Lewis Carroll, “Alice’s Adventures in Wonderland” In the early 16th century, a Swiss ...
Objective To identify the optimal dose and type of physical activity to improve functional capacity and reduce adverse events in acutely hospitalised older adults. Design Systematic review and ...
Objectives To investigate the dose–response association of aerobic physical activity (PA) and muscle-strengthening exercise (MSE) with all-cause mortality. Methods National Health Interview Survey ...
Cleveland Clinic researchers are working to improve the way we use evolutionary modeling to understand drug resistance. The study, published in Science Advances, uses a new type of evolutionary model ...