Web site accessibility has been a lingering issue that is still present even on modern websites. To make a website accessible, its elements should be "readable" and "understandable" by a screen reader ...
You should enable JavaScript on an iPad so that websites you access function properly and so features like animations and videos work.
JavaScript isn't replacing Office macros anytime soon, but the Office Web apps (and the SharePoint-based enterprise equivalents) are improving regularly. For users that means simple but useful ...