A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...

Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by ...

Animals such as spiders make fibers which are strong and elastic. These fibers have a polypeptide structure and serve as inspiration for research into the development of functional materials.

Ozempic has been making headlines for its remarkable success in treating obesity and diabetes. Yet it is just one in a rapidly growing class of drugs called peptide therapeutics that sits between ...

Fibrous structures act as load-bearing components in vivo in many natural proteins besides enzymes, which are soluble globular molecules. Natural evolutionary processes have produced structural ...