Monoclonal antibody expression systems typically utilise a signal peptide to ensure secretion of the antibody into the cell culture medium. Although this reduces the complexity of purification and ...
Scaling-up production of lentiviral vectors (LV)-based therapies is a persistent challenge for biomanufacturers, and one that threatens their development unless commercial-scale production ...
Optimizing the clarification of cell culture or fermentation broth is generally seen as a limited contributor to critical quality attributes (CQA). Researchers at Merck, however, say it’s time to ...
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