Building functional human muscle in the laboratory has long been a goal of regenerative medicine, but one stubborn obstacle ...

A. Fluorescent immunostaining of PDGFRα, showing mesenchymal progenitors, laminin surrounding skeletal muscle, and AR. Arrows indicate mesenchymal progenitors expressing AR, arrowheads indicate ...

The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation. Acting as ...

A new study has observed differences in the shape, structure and mechanical properties of nuclei in trained and untrained individuals, potentially helping to explain the anti-aging effects of exercise ...

Researchers identified a critical AMPK phosphorylation site that regulates mitochondria, muscle contraction, and sugar ...

Neuromuscular disorders can be caused by hereditary or acquired genetic mutations, impairing the function of skeletal muscles: those under voluntary control. These diseases cause muscles to weaken and ...

Mice retained normal muscle function and health even though their NAD+ levels were reduced by 85%, according to new research from the University of Copenhagen. Given that NAD levels drop by only up to ...

A recent research study found that a combination of the GLP-1 receptor agonist semaglutide and bimagrumab, an antibody that blocks activin signaling pathways, results in greater weight loss while also ...

Girish Melkani, Ph.D., recently promoted to professor in the Department of Pathology, has been named the latest recipient of the school’s Featured Discovery award. This recognition celebrates notable ...

“Instead of inserting the corrected piece of information, we used CRISPR to cut DNA in two strategic places,” study coauthor Dwi Kemaladewi, a research fellow at the Hospital for Sick Children (Sick ...